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So far Flavio Rump has created 12 blog entries.

Open Source Drug Discovery with M4K Pharma’s Owen Roberts

TL;DR Drug Discovery is expensive and risky Cost and Risk can be lowered by more collaboration and sharing M4K Pharma is proposing Open Source Drug Discovery Don’t file patents and share all your data Academics and CRO’s start helping with development Data filed with regulatory package still allows you to have exclusivity M4K Pharma will be able to recoup costs through this exclusivity Trust between [...]

By | 2018-04-17T22:16:15+00:00 April 17th, 2018|Uncategorized|0 Comments

Opening up the opaque Peer Review Process with Sam & Daniela from PREreview

TL;DR Peer review is a fundamental building block of science Most scientists receive no formal on training on how to conduct peer review Sharing critical feedback with senior researchers can be intimidating for young scientists Journal club meetings are an important way for scientists to learn about new science and how to critically assess science Feedback generated in those meetings currently is lost to the [...]

By | 2018-04-09T02:22:27+00:00 April 9th, 2018|Collaboration|0 Comments

How collaborating with robots will speed up biomedical research with Oskari Vinko

  TL;DR Big bottleneck in biomedical research is tedious routine work done by highly educated researchers Current lab automation solutions are much behind what automation is possible in other fields like self driving cars UniteLabs is working on a ‘plug-and-play’ solution for scientists who don’t want to spend weeks coding and setting up robots in their labs They are already deploying their technology at Idorsia [...]

By | 2018-03-28T19:19:04+00:00 March 28th, 2018|automation, Collaboration|0 Comments

How the Gates Foundation is reshaping how science gets published with Ashley Farley

TL;DR Gates Open Research is a publishing & research platform for Gates Grantees They don’t editorialize and let scientists decide what is worthy of publication It is a living document with version control, meaning publications can be improved if new data becomes available in a transparent manner. An open peer review process makes sure it is scientifically sound while allowing for greater transparency for scientists [...]

By | 2018-03-02T23:18:30+00:00 March 2nd, 2018|Collaboration|0 Comments

Translating Science from Academia and the Future of Medicine with Prof. Ernst Hafen – Part 2

This is the second part of an interview we had the chance to do with Prof. Ernst Hafen. The first part centers around how Citizen Science can shape drug discovery and his initiative midata.coop. Listen to the podcast here. TL;DR The birth of the Bio-Technopark Schlieren shows that if innovative entrepreneurs come together with great scientists, magic can happen. Big bottleneck in translating science from [...]

By | 2018-02-14T00:11:10+00:00 February 14th, 2018|Uncategorized|0 Comments

Protocols.io – Speeding up biomedical research by sharing protocols with Lenny Teytelman

TL;DR Protocols.io - a collaborative, open access platform to share scientific recipes. Scientific reproducibility is likely no worse than 30 years ago, but because of increased scrutiny and better technology now available, we are getting better at addressing it. In traditional peer review, reviewers don’t verify the working of protocols. But on protocols.io, the community has a chance to directly run the protocol and confirm [...]

By | 2018-02-07T11:03:22+00:00 February 7th, 2018|Uncategorized|0 Comments

How Citizen Science can Transform Drug Discovery with Ernst Hafen

This is part 1 of a longer interview with Prof. Ernst Hafen TL;DR Citizens can store their medical data on a not-for-profit service called midata.coop The service is organized as a Swiss cooperative, owned by the members Patients can share their data on a case by case basis with doctors and clinical studies This could help reduce the time & money spent to recruit patients [...]

By | 2018-02-04T16:44:29+00:00 February 4th, 2018|Uncategorized|0 Comments

Open Research in the Wild: How to get the most out it with Rachel Harding

TL;DR Doing open research and having an open lab notebook has many benefits Shortens delay of dissemination Builds trust between researchers Can start fruitful mentorship and collaborative efforts On the downside, there is a small chance of your work getting scooped Mostly applicable now in areas with smaller research communities Publishing in high-impact journal still matters, even for open research scientists Dr. Rachel Harding is [...]

By | 2018-01-27T13:27:41+00:00 January 26th, 2018|Collaboration|0 Comments

The Biggest Challenges in Cancer Research & How to Use ML to do Drug Discovery with Sarah Constantin

TL;DR Drug Discovery using machine learning is working and holds great promise Most cancer treatments are incredibly expensive and only extend life by a few months Cancer research started when in WWII it was discovered mustard gas could cause tumor regression Lack of diversity in approaches is one of the main bottlenecks A lot of friction between a researcher with a great idea and getting [...]

By | 2018-01-24T02:19:08+00:00 January 24th, 2018|Collaboration, Funding|0 Comments

Why 85% of health research is wasted with Paul Glasziou

TL;DR 85% of biomedical research is wasted 50% of it because it never gets published of the remaining, another 50% because publication is not complete and applicable of the remaining, another 50% because study includes fixable design flaws and lacks systematic review of literature Several initiatives underway to fix the issues, of technological and financial nature. Some funders achieve 98% publication rates. Technological tools assist [...]

By | 2018-01-12T13:47:01+00:00 January 12th, 2018|Collaboration, Funding|0 Comments