In Bio2040’s latest episode we had the chance to talk to Sam Lee, a long-time veteran of the biotech space. He is currently working in the R&D program management at Bio-N-Tech and recently set up the IndieBio incubator in New York. Before that, Sam has been working as a Head of Innovation at Dr. Reddy’s Laboratories, has worked as a management consultant and pharma research [...]
Challenges and Opportunities in Translating Innovation with Nadine C. Martin TL;DR sitem-insel AG is a public private partnership designed to support and to accelerate translational medicine It also helps scientists and professionals in life sciences by educating them in bio-entrepreneurship, establishing collaboration amongst partners (e.g academia, industry) and supports them when dealing with regulatory affairs challenges Lots of scientists struggle with the basics on how [...]
TL;DR Incentives are distorted Prestige through high impact journals is not pareto optimal. SEED is an interdisciplinary conference to tackle this problem through technology Attributing reputation to single observations & units of work instead of research paper could be a way forward Many interesting propositions exist to build alternative reputation systems Who is Aleksandra Sokolowska? Head of Research & Analytics Validity Labs Computational Scientist & [...]
TL;DR Drug Discovery is expensive and risky Cost and Risk can be lowered by more collaboration and sharing M4K Pharma is proposing Open Source Drug Discovery Don’t file patents and share all your data Academics and CRO’s start helping with development Data filed with regulatory package still allows you to have exclusivity M4K Pharma will be able to recoup costs through this exclusivity Trust between [...]
TL;DR Peer review is a fundamental building block of science Most scientists receive no formal on training on how to conduct peer review Sharing critical feedback with senior researchers can be intimidating for young scientists Journal club meetings are an important way for scientists to learn about new science and how to critically assess science Feedback generated in those meetings currently is lost to the [...]
TL;DR Big bottleneck in biomedical research is tedious routine work done by highly educated researchers Current lab automation solutions are much behind what automation is possible in other fields like self driving cars UniteLabs is working on a ‘plug-and-play’ solution for scientists who don’t want to spend weeks coding and setting up robots in their labs They are already deploying their technology at Idorsia [...]
TL;DR Gates Open Research is a publishing & research platform for Gates Grantees They don’t editorialize and let scientists decide what is worthy of publication It is a living document with version control, meaning publications can be improved if new data becomes available in a transparent manner. An open peer review process makes sure it is scientifically sound while allowing for greater transparency for scientists [...]
This is the second part of an interview we had the chance to do with Prof. Ernst Hafen. The first part centers around how Citizen Science can shape drug discovery and his initiative midata.coop. Listen to the podcast here. TL;DR The birth of the Bio-Technopark Schlieren shows that if innovative entrepreneurs come together with great scientists, magic can happen. Big bottleneck in translating science from [...]
TL;DR Protocols.io - a collaborative, open access platform to share scientific recipes. Scientific reproducibility is likely no worse than 30 years ago, but because of increased scrutiny and better technology now available, we are getting better at addressing it. In traditional peer review, reviewers don’t verify the working of protocols. But on protocols.io, the community has a chance to directly run the protocol and confirm [...]
This is part 1 of a longer interview with Prof. Ernst Hafen TL;DR Citizens can store their medical data on a not-for-profit service called midata.coop The service is organized as a Swiss cooperative, owned by the members Patients can share their data on a case by case basis with doctors and clinical studies This could help reduce the time & money spent to recruit patients [...]